… associations between mLOY and clinical measures, here the composition of the classical
hematologic compartments in the UK Biobank, … to evaluate the association of mLOY with blood …

… the Applied Biosystems UK BiLEVE or UK Biobank Axiom array. … mosaic Y loss events were
performed as described previously [46]. In brief, log transformed intensities from UK Biobank …

… of mLRR-Y scores estimated in 245,349 women from the UK Biobank study (Supplementary …
This did not produce any significant associations after Bonferroni correction across the 156 …

… associated with incidence of solid tumors in the UK Biobank, … and mortality in the UK Biobank
also noted an association … of cells affected by mLOY and increased risk of mortality (17). …

… Mosaic loss of Y chromosome (LOY) is the state of nullisomy … is a significant risk factor for
future mortality and various types of … in the UK Biobank project [8]. The effect size for these 156 …

… , the association between the mosaic loss of the Y chromosome and … UK Biobank. In contrast,
the relative risk per 1% increase of detectable loss of Y chromosome and the risk of death …

… We want to acknowledge the participants and investigators of the United Kingdom Biobank,
Biobank Japan, and PRACTICAL consortium. We thank the staff of the Department of …

… Third, we did not test whether our results were influenced by mosaic loss of Y chromosome
(mLOY). Older men and men with unhealthy lifestyles tend to experience a greater degree of …

… is associated with increased risk for all-cause mortality and a … men aged 70 years in the UK
Biobank were affected by LOY at … In this study, we examined the predictive performance of a …

… The development of new biomarkers for prediction and early … UK Biobank, an association
was found between mosaic loss … is a significant risk factor for mortality and various diseases in …